![]() That compares to nearly 16% weight loss of those on the higher dose, or about 34 pounds, and 3% or 7 pounds among those getting the placebo. Those on the lower dose lost about 13% of their body weight, or about 30 pounds. The new trial included 938 adults, one-third of whom received a 10-mg dose of tirzepatide, one-third received a 15-milligram dose, and one-third a placebo. Ozempic, Wegovy, Mounjaro : How these medications promote weight loss What did the new trial show? Lilly is currently in the planning stages for one, Ahmad saidīoth semaglutide and tirzepatide are delivered by weekly injection. Semaglutide, the generic name for the drug in both Ozempic and Wegovy, acts only on the first of those and thus appears to be slightly less effective at promoting weight loss, though they have never been compared in a head-to-head study. It is believed to act on obesity in two ways, Ahmad said, by reducing appetite and affecting how the body burns fat. Tirzepatide, sold under the brand name Mounjaro, is approved for the treatment of diabetes. More: Experts worry the 'magic' in new weight loss medications carries a dark side What is tirzepatide and how does it compare to Ozempic and Wegovy? ![]() Ahmad said Lilly plans to release full results at the American Diabetes Association's annual meeting in San Diego in June and submit them to a peer-reviewed journal. ![]() So far, data on the drug has only been released via a company news release. It is generally harder for people with diabetes to lose weight and this is the first drug trial to show such significant weight loss for people with the disease, according to Lilly associate vice president Dr. The company had already shown that the same drug, generically called tirzepatide, could help people with obesity but not diabetes lose more than 20% of their body weight. The study, released by drug-maker Eli Lilly on Thursday, showed participants with diabetes lost nearly 16% of their weight over the 18-month trial. The drug is not yet approved for weight loss, but likely will be later this year, now that two trials have found it effective with similar side effects as other weight loss medications. In a second large study, the drug Mounjaro, now used to treat diabetes, has shown its effectiveness at helping people lose weight.
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